From FFG's Chris:
The Cthulhu genre is among the most recognized and well-regarded in the gaming hobby, and we hope to provide a fast, clever, and horrific collectible card game in this juicy setting, complete with 1920’s paranormal investigations, jaded detectives, mad cultists, and horrors from beyond the stars.
From the press release:
The CALL OF CTHULHU CCG will have no relation or compatibility to the Mythos Collectible Card Game published by Chaosium, Inc in the late 1990’s. Fantasy Flight’s CALL OF CTHULHU CCG will present new and innovative game play which will be simply, fast, and yet provide a deep and dynamic experience for players. The CALL OF CTHULHU CCG will seek to inspire the wonderful flavor of the Cthulhu genre, such as the flavorful "pulp" 1930’s environment, arcane tomes and secrets, paranormal investigations, the elder gods and their terrible servants, dark sinister plots, inhuman conspiracies, and dangers from beyond the stars.
Call of Cthulhu: The Card Game