Players all control the Powerpuff Girls on their turns via a neat card mechanism: Cards are selected and revealed at the same time, but enacted according to times printed on them. It basically comes down to wandering about the board, revealing villain tiles and battling them with the Powerpuff Girls with the goal of being the first player to capture 4 villains.
The villains are captured by way of die rolls. Each girl has an identical die, so the more of the girls you have present to combat a villain, the better your odds of capture. ...of course, the better your odds of getting some of them knocked out for the rest of the turn. Since everyone shares the girls, having the earliest time card, and getting the girls knocked out will impact everyone.