It'll work, but much of the fun will vanish. I think there was a two-player variant published in THE GENERAL...
There is a solitaire and two player variant in the GENERAL Vol 29, No 6. (1995).
2 player uses pretty much standard rules. There is a random draw of loyalty, so that bth players might be fighting for th sam side. When Revolution card is drwan, both players discard loyalty markers and and pick another at random. Game lasts once thru the deck.