My gaming group spent quite a while having the exact same conversation after we played out first 6-player game. The pressure is on when you're in the middle, but if your diplomacy skills are good, you'll do great in the center. My only recommendation is that you don't stick a newbie in the center on his first try.
Antike is genius, my gaming group hasn't been so unanimously thrilled about a game in a really long time. We literally played the whole game, standing. That has never happened before. And we immediately played a second game, staying up to 1:30am - a gaming club late-night record.

Just like in Diplomacy, we were running off to corners of the room negotiating with other players, making and breaking alliances. This is why I believe (after playing a 6 & 3 player game) Antike is most definitely best with 5-6 players. I love the negotiation mechanic in games, and cunning negotation is a must if you wish to win at 6-player Antike.
Unlike many war games, Antike is about well-planned, concise battles. It's similar to Wallenstein in this respect. You can't just go around fighting with whomever, whenever. And this is one of the reasons why I love Antike so much.
Soon everyone will hear about Antike and will be playing, I predict it's gonna be huge. And I think this would be great with even 7-8 players because it plays so fast. Mac, any thoughts about creating a 7-8 player expansion with new maps and pieces? Congrats on an incredible game!