For instance the 3, 4, and 5 player 1856 games are distinctly different in style and strategy/approach to being successful. The 6 player game, I have only played one, seems to be very similar in style to the 5 player game.
This is where the line between strategy and review gets blurred. Brian Bankler(Bankler) http://www.boardgamegeek.com/thread/90092 does a great job of reviewing 1856 and I don’t want to cover ground already well covered so I want to focus on some of the techniques and strategies I employ to be successful. I have now played 1856 well over a dozen times with a wide variety of outcomes. At least twice I went bankrupt, won 3 or 4, and was competitive in the others but just didn't get over the hump. Those where I was competitive and I could not get over the hump were those games where I allowed a powerful private and public combo early.
I don’t think enough focus has been applied to the importance of “Priority” and the value of the private companies in combonation with the public companies. Taken individually the Flos, W&S, and CC are non critical. Their income and tile lay options are interesting and sometimes useful but rarely critical. The Great Lakes, the Niagra Falls, and St. Clair all have potentially critical roles that can be played in combination with Public Companies.
The combos of Niagra and Wellend, LPS and St. Clair, and Great Lakes with any of LPS, GW, or Welland are powerful. This is where jockeying in the Private auction and engineering first stock round priority comes into play. I feel that allowing LPS and Great Lakes together is a starting position that all players should not allow a strong player to have. I personally feel that the Great Lakes Shipping Company should sell for no less than $120 to any player. Anything under that is a steal. The Great Lakes Company has the potential to be useful to LPS, GW, and WR as soon as phase 2 starts.
There are a couple ways to guard against a solid combo gaining too much of an advantage early.
1. The playing of a #5 Tile is generally key to the success of leveraging +10 for off board locations early. This means if a powerful combo exists, then players must use up the #5 tiles before the powerful combo can get to them. There are two of them.
2. LPS or WR get going faster by getting to play green tiles and being able to buy the off board +10 bonus from Public Companies. Try to prevent this by selecting to buy those private companies into public after they have operated in the second OR or delaying their purchase another set of OR’s.
If you have not gotten the hint yet that you often must work against your fellow gamers to be successful in this game or other 18XX games, please note: you have been warned

I nearly always bid on the Great Lakes Company the first round of the private auction unless the price is already above $125. AS the private auction develops pay close attention to who will have priority. Make deals to prevent the owner of the Great Lakes from getting LPS or WR. Jane, I will buy St. Clair if you open LPS next. I have done this and won with that type of strategy.
Some other hints:
Pay attention to priority. After the first stock round Priority is most useful in the late middle and end game because during those stock rounds you want to get the first pick after the OR of those companies that are generating the best Revenue or of opening your second or third company.
Pay attention to phase control. If you can initiate a phase and it clearly will hinder an opponent more than yourself, you should initiate the phase change. Also, being the person who buys the first six train is often better than not.
Count on the fact that there will be the second issuance of CGR Shares, that way if only ten go, you will be happily surprised.
I have never seen the person who opened the WR as their first company go on to win the game. I have seen them come in second a fair amount though

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