Three Galaxies is the space opera setting for the Palladium Megaverse, and also tied to the story of the Rifts setting. Besides the titular three galaxies, the setting encompasses dozens of powerful nations and corporations, thousands of sentient races, tens of thousands of worlds, and trillions of beings. All the supernatural and superscience capabilities of the Palladium Megaverse are available (and omnipresent) in the Three Galaxies; merchants and adventurers alike travel in starships whose speeds are measured in light years per hour, and avail themselves of advanced magic, psionics, and technology.
The core conflict in the Three Galaxies setting is between the Consortium of Civilized Worlds (the "good" side) and the Transgalactic Empire (the "evil" side). Other key factions in this conflict include weapon manufacturing dynasty Naruni Enterprises, the hedonistic Paradise Federation, the manipulative Splurgoth kingdoms, the fantastic United Worlds of Warlock, and the divided Wolfen Empire, to name a few.