Nightshade (1985)

Nightshade is a ZX Spectrum video game developed and released by Ultimate Play The Game in 1985. Building upon the earlier titles Knight Lore and Alien 8 using the flip-screen, isometric gameplay branded Filmation, Nightshade introduces a scrolling isometric environment branded Filmation II.

The player takes the role of a knight who enters the plague-ridden village of Nightshade to vanquish four demons who hold sway over it. Similarly to the major foes in Atic Atac, each demon is vulnerable to a particular object which must be collected by the player (a hammer, a Bible, a crucifix and a hourglass). To help the player locate the demons, these objects also glow when in close proximity to the demon they destroy.

Source: Wikipedia, "Nightshade (1985 video game)", available under the CC-BY-SA License.