Queen Myrrah is the creator and leader of the Locust Horde during the Revolutionary, Lambent, and Locust Wars, and then continued to lead the remaining loyal Locust Horde forces during the Lambent Pandemic. Myrrah was the child of an Imulsion miner and was born with an immunity to the effects of Imulsion. She was brought to the New Hope Research Facility as a subject to help treat other children of Imulsion miners infected with Rustlung, led by Dr. Niles Samson. Through genetic experiments, Myrrah's embryonic stem cells were responsible for the creation of the Locust Horde. Myrrah eventually conceived a daughter, Reyna, with scientist Dr. Torres, but was led to believe by Niles that Reyna was killed during an escape attempt by Torres. Myrrah, furious, led the Locust to slaughter all the scientists, including Niles, and to become an independent race.