Skizzo was from California, either in Sacramento or Fresno. He attended college and graduated with honors. Skizzo would later lied and bragged of being a gangbanger and having smuggled drugs and guns from California to Oregon.
After the Freaker Virus decimated the world, Skizzo ended up at the Lost Lake camp lead by Iron Mike, eventually earning the role of head of security. Though he was frequently at odds with everyone else in the camp, partially due to him abusing his authority. When Iron Mike formed a treaty with the Rest In Peace cult's leader Carlos, Skizzo objected, as he considered the Rippers to be no longer human and would inevitably betray the treaty.